Announcement PDF 604 page 1/2 Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder To Company Name/Scheme Acrux Limited ACN/ARSN ACN: 082 001 152 1. Details of substantial holder (1) Name Phillip Asset Management Ltd atf BioScience Managers Translation Fund I ACN/ARSN (if applicable) N/A There was a change in the interests of the substantial holder on 19/12//2024 The previous notice was given to the company on 24/12/2020 The previous notice was dated 29/12/2020 2. Previous and present voting power The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in when last required, and when now required, to give a substantial holding notice to the company or scheme, are as follows: Class of securities (4) Previous notice Present notice Ordinary Person’s votes Voting power (5) Person’s votes Voting power (5) 31,147,134 15.09% 37,561,419 10.32% Nature of change (6) Consideration given in relation to change (7) Class and number of securities affected 3. Changes in relevant interests Date of change Person whose relevant interest changed 12/12/24 Phillip Asset Management Ltd atf BioScience Managers Translation Fund I Phillip Asset Management Ltd atf BioScience Managers Translation Fund I 19/12/24 Person’s votes affected Holding Diluted due to the issue of new shares Share Placement $200,000 5,714,285 5,714,285 4. Present relevant interests Particulars of each relevant interest of the substantial holder in voting securities after the change are as follows: Holder of relevant interest Registered holder of securities Person entitled to be registered as holder (8) Nature of relevant interest (6) Class and number of securities Phillip Asset Management Ltd atf BioScience Managers Translation Fund I Phillip Asset Management Ltd atf BioScience Managers Translation Fund I N/A Ordinary 37,561,419 Person’s votes 10.32% 604 page 2/2 5. Changes in association The persons who have become associates (2) of, ceased to be associates of, or have changed the nature of their association (9) with, the substantial holder in relation to voting interests in the company or scheme are as follows: Name and ACN/ARSN (if applicable) Nature of association N.A 6. Addresses The addresses of persons named in this form are as follows: Name Phillip Asset Management Ltd atf BioScience Managers Translation Fund I Signature print name Jessica Bell Address Level 5, 45 William Street, Melbourne, VIC Craig Semmens capacity: Director date sign here 19/12/2024 DIRECTIONS (1) If there are a number of substantial holders with similar or related relevant interests (eg. a corporation and its related corporations, or the manager and trustee of an equity trust), the names could be included in an annexure to the form. If the relevant interests of a group of persons are essentially similar, they may be referred to throughout the form as a specifically named group if the membership of each group, with the names and addresses of members is clearly set out in paragraph 6 of the form. (2) See the definition of “associate” in section 9 of the Corporations Act 2001. (3) See the definition of “relevant interest” in sections 608 and 671B(7) of the Corporations Act 2001. (4) The voting shares of a company constitute one class unless divided into separate classes. (5) The person’s votes divided by the total votes in the body corporate or scheme multiplied by 100. (6) Include details of: (a) any relevant agreement or other circumstances because of which the change in relevant interest occurred. If subsection 671B(4) applies, a copy of any document setting out the terms of any relevant agreement, and a statement by the person giving full and accurate details of any contract, scheme or arrangement, must accompany this form, together with a written statement certifying this contract, scheme or arrangement; and (b) any qualification of the power of a person to exercise, control the exercise of, or influence the exercise of, the voting powers or disposal of the securities to which the relevant interest relates (indicating clearly the particular securities to which the qualification applies). See the definition of “relevant agreement” in section 9 of the Corporations Act 2001. (7) Details of the consideration must include any and all benefits, money and other, that any person from whom a relevant interest was acquired has, or may, become entitled to receive in relation to that acquisition. Details must be included even if the benefit is conditional on the happening or not of a contingency. Details must be included of any benefit paid on behalf of the substantial holder or its associate in relation to the acquisitions, even if they are not paid directly to the person from whom the relevant interest was acquired. (8) If the substantial holder is unable to determine the identify of the person (eg. if the relevant interest arises because of an option) write “unknown”. (9) Give details, if appropriate, of the present association and any change in that association since the last substantial holding notice.